PHENETHYLZINC BROMIDE Property

Boiling point:

65 °C

Density 

0.965 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

2-8°C

Water Solubility 

Reacts with water.

Sensitive 

Air Sensitive

Exposure limits

ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)

CAS DataBase Reference

308796-14-7

Safety

Hazard Codes 

F,Xn

Risk Statements 

14-19-22-36/38-40-36/37-11

Safety Statements 

16-26-33-36-36/37

RIDADR 

UN 2056 3/PG 2

WGK Germany 

1

HazardClass 

4.3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H261In contact with water releases flammable gas

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H319Causes serious eye irritation

H333May be harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

PHENETHYLZINC BROMIDE Chemical Properties,Usage,Production

Uses

Phenethylzinc bromide can be used as a reagent:

• In the transition metal-catalyzed Negishi cross-coupling reaction to prepare aryl or heteroaryl derivatives by reacting with organic halides or triflates via carbon-carbon bond formation.
• To prepare (4-phenyl-1-butyn-1-yl)benzene by reacting with phenylacetylene via palladium-catalyzed cross-coupling reaction.
• To synthesize benzyl substituted thienopyrimidine derivatives.